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Understanding Angiosarcoma: A Rare and Aggressive Form of Cancer

Created by Mbaka Joshua in Health and Medicine 31 May 2023

Angiosarcoma is an extremely rare and aggressive type of cancer that originates in the endothelial cells lining blood vessels or lymphatic vessels. It can manifest in various parts of the body, including the skin, breast, liver, and other organs. Angiosarcoma is characterized by the uncontrolled and abnormal growth of these cells, leading to the formation of malignant tumors.


The precise cause of angiosarcoma is often unknown, although certain risk factors have been identified. One such factor is prior radiation therapy, especially in cases where high doses were administered. Exposure to certain chemicals like vinyl chloride or arsenic has also been associated with an increased risk of developing angiosarcoma. Additionally, chronic lymphedema, a condition characterized by persistent swelling due to impaired lymphatic drainage, is a known risk factor. Some individuals may have an inherited predisposition to angiosarcoma, as certain genetic conditions like hereditary lymphedema or specific genetic mutations have been linked to its occurrence.


The presentation and symptoms of angiosarcoma can vary depending on the affected site. In the skin, angiosarcoma often presents as a purplish or reddish patch or lump that may be tender, itchy, or bleed easily. When angiosarcoma occurs in internal organs, the symptoms may include pain, swelling, and dysfunction of the affected organ.


Diagnosing angiosarcoma typically involves a comprehensive evaluation that incorporates medical history, physical examination, imaging tests, and a biopsy of the affected tissue. Imaging techniques like MRI, CT scan, or ultrasound help in visualizing the tumor and determining its extent. A biopsy is crucial for confirming the presence of angiosarcoma and involves the removal of a small tissue sample for microscopic examination.


Treatment options for angiosarcoma depend on factors such as the location, stage, and overall health of the individual. Surgical intervention to remove the tumor is often the primary approach if the tumor is localized and operable. However, complete surgical removal may not always be possible, especially when the tumor has spread extensively or is in a delicate location. In such cases, other treatment modalities like radiation therapy and chemotherapy are employed. Radiation therapy utilizes high-energy beams to target and destroy cancer cells, while chemotherapy uses drugs to kill cancer cells or inhibit their growth. In some instances, a combination of surgery, radiation, and chemotherapy may be recommended to achieve the best outcome.


Angiosarcoma is notorious for its aggressive nature and has a generally poor prognosis. The prognosis can vary depending on factors such as the stage of cancer at diagnosis, the location of the tumor, and the overall health of the individual. Unfortunately, due to its rarity and the challenges it poses in treatment, the long-term survival rates for angiosarcoma remain relatively low.


If you suspect the presence of angiosarcoma or have concerns about any symptoms, it is essential to consult with a healthcare professional promptly. They can provide an accurate diagnosis, personalized treatment plan, and the most up-to-date information regarding angiosarcoma. Early detection and intervention can significantly improve the chances of successful treatment and better outcomes for individuals affected by this aggressive cancer.


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